A View to a Kill: Structure of the RNA Exosome
نویسندگان
چکیده
The exosome is a 3' to 5' exoribonuclease central to many cellular processes, including mRNA decay. now present the biochemical reconstitution and crystal structure of the eukaryotic exosome. This remarkable achievement provides key insights into the composition and assembly of the human and yeast exosomes, revealing functions of individual subunits.
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عنوان ژورنال:
- Cell
دوره 127 شماره
صفحات -
تاریخ انتشار 2006